Zhou Li-juan, Lyu Zhong-fa
Department of Dermatology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2015 Jul;44(4):465-70. doi: 10.3785/j.issn.1008-9292.2015.07.18.
Asteatotic dermatitis (AsD) is a common skin disease characterized by dry skin, itching, erythema, peeling and other skin lesions. It results from the damage in cutaneous barrier related to age, seasonal climate and bathing habits, and presents dysfunction of sebaceous, sweat glands and the increase of transepidermal water loss. The pathogenesis of AsD is not clear. Previous studies mainly focused on the relationship between skin barrier damage and bathing habits, age or gender. Recently, more studies focus on its relationship with other systematic diseases and drugs. This paper reviews etiology and pathogenesis of AsD to provide new ideas for the diagnosis and treatment of AsD.
乏脂性皮肤炎(AsD)是一种常见的皮肤病,其特征为皮肤干燥、瘙痒、红斑、脱屑及其他皮肤损害。它是由与年龄、季节气候及沐浴习惯相关的皮肤屏障受损所致,表现为皮脂腺、汗腺功能障碍及经皮水分流失增加。AsD的发病机制尚不清楚。既往研究主要聚焦于皮肤屏障损伤与沐浴习惯、年龄或性别的关系。近来,更多研究关注其与其他系统性疾病及药物的关系。本文综述AsD的病因及发病机制,为AsD的诊断和治疗提供新思路。