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直肠癌中直肠系膜淋巴结受累情况的术前评估

Preoperative assessment of mesorectal lymph node involvement in rectal cancer.

作者信息

Beynon J, Mortensen N J, Foy D M, Channer J L, Rigby H, Virjee J

机构信息

Department of Surgery, Bristol Royal Infirmary, UK.

出版信息

Br J Surg. 1989 Mar;76(3):276-9. doi: 10.1002/bjs.1800760320.

DOI:10.1002/bjs.1800760320
PMID:2655811
Abstract

One hundred patients with rectal adenocarcinoma were examined preoperatively with rectal endosonography (ES) and 50 were also examined with computed tomography (CT). ES predicted mesorectal lymph node involvement with an accuracy of 83 per cent, sensitivity of 88 per cent, specificity of 79 per cent, positive predictive value of 78 per cent and negative predictive value of 89 per cent. CT in comparison had an accuracy of 57 per cent, sensitivity of 25 per cent, specificity of 91 per cent, positive predictive value of 75 per cent and negative predictive value of 53 per cent. No particular histological architectural feature could be identified as responsible for false positive diagnosis though nodal size was significantly larger in the true positive and false positive group when compared with the true negatives (P less than 0.001 and P less than 0.01 respectively).

摘要

对100例直肠腺癌患者进行了术前直肠内超声检查(ES),其中50例还进行了计算机断层扫描(CT)检查。ES预测直肠系膜淋巴结受累的准确率为83%,敏感性为88%,特异性为79%,阳性预测值为78%,阴性预测值为89%。相比之下,CT的准确率为57%,敏感性为25%,特异性为91%,阳性预测值为75%,阴性预测值为53%。尽管与真阴性组相比,真阳性组和假阳性组的淋巴结大小明显更大(分别为P<0.001和P<0.01),但未发现可导致假阳性诊断的特定组织学结构特征。

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