Dória Maíra Teixeira, Maesaka Jonathan Yugo, Martins Sebastião Nunes, Silveira Thales Parenti, Boufelli Gabriela, Siqueira Sheila Aparecida Coelho, Baracat Edmund Chada, Filassi José Roberto
Department of Obstetrics and Gynecology - Faculdade de Medicina - Universidade de São Paulo, São Paulo/SP - Brazil .
Department of Pathology - Faculdade de Medicina - Universidade de São Paulo, São Paulo/SP - Brazil .
Autops Case Rep. 2015 Sep 30;5(3):49-53. doi: 10.4322/acr.2015.018. eCollection 2015 Jul-Sep.
Gastrointestinal metastases from breast cancer are rare and generally occur several years after the diagnosis of the primary lesion. The diagnosis of gastric metastasis as the initial presentation of breast cancer is even rarer and can potentially mimic gastric carcinoma. We report the case of a 66-year-old female patient submitted to a total gastrectomy because of the histological diagnosis of undifferentiated gastric carcinoma. During the surgical procedure, biopsies of the peritoneum and the liver were performed, which were consistent with metastatic breast invasive lobular carcinoma (ILC). The primary lesion of the breast was detected during the post-operative period, when a 4-cm-long lesion was detected on physical examination and mammography. The revision of the gastric biopsy confirmed the diagnosis of ILC. The authors call attention to the rarity of gastrointestinal metastases as the initial presentation of breast ILC.
乳腺癌的胃肠道转移罕见，通常在原发性病变诊断后数年发生。以胃转移作为乳腺癌的首发表现的诊断更为罕见，且可能酷似胃癌。我们报告一例66岁女性患者，因组织学诊断为未分化胃癌而接受了全胃切除术。在手术过程中，对腹膜和肝脏进行了活检，结果与转移性乳腺浸润性小叶癌（ILC）相符。术后期间发现了乳腺的原发性病变，当时体格检查和乳房X线摄影发现一个4厘米长的病灶。对胃活检标本的复查证实了ILC的诊断。作者提醒注意胃肠道转移作为乳腺ILC首发表现的罕见性。
