Anguiano-Albarran Ricardo, Obi Franklin, Pradeep Sidart, Cain Daniel, Bartlett Bryan, Simien Melvin
Internal Medicine, Baylor Scott & White All Saints Medical Center, Fort Worth, USA.
Pathology, Baylor Scott & White All Saints Medical Center, Fort Worth, USA.
Cureus. 2023 Jun 13;15(6):e40371. doi: 10.7759/cureus.40371. eCollection 2023 Jun.
Invasive lobular carcinoma (ILC) is the second most common subclass of breast cancer and adds to the breast malignancy burden in women.Studies focused on metastatic patterns of ILC have reported bone, gynecologic organs, the peritoneum, and the gastrointestinal tract as potential sites of metastasis. Metastatic spread to the stomach has been reported, but generally remains an infrequent finding. Due to vague symptomatology and the visual limitations of endoscopic examination, metastatic lesions can often mimic a primary gastric malignancy. Metastasis in the stomach can be challenging to diagnose and requires a multimodal, thorough endoscopic and immunohistochemical evaluation. It is important to distinguish the primary origin of malignant lesions as treatment can range from systemic chemotherapy to surgical resection based on the diagnosis. We present a case of an underlying ILC metastatic lesion mimicking a primary gastric adenocarcinoma.
浸润性小叶癌（ILC）是乳腺癌的第二大常见亚型，增加了女性乳腺癌的恶性负担。针对ILC转移模式的研究报告称，骨骼、妇科器官、腹膜和胃肠道是潜在的转移部位。已有胃转移的报道，但总体上仍然是罕见的发现。由于症状模糊以及内镜检查的视觉局限性，转移病灶常常可模仿原发性胃恶性肿瘤。胃转移灶的诊断可能具有挑战性，需要进行多模式、全面的内镜和免疫组化评估。区分恶性病变的原发部位很重要，因为根据诊断，治疗方法可以从全身化疗到手术切除不等。我们报告一例潜在的ILC转移灶模仿原发性胃腺癌的病例。
