班努地区重型β地中海贫血患者的近亲结婚率。
Consanguinity ratio in b-thalassemia major patients in District Bannu.
作者信息
Khan Muhammad Sadiq, Ahmed Mushtaq, Khan Rahmat Ali, Mushtaq Nadia, Wasim Ullah Shah Muhammad
机构信息
Department of Biotechnology, University of Science and Technology, KPK, Pakistan.
出版信息
J Pak Med Assoc. 2015 Nov;65(11):1161-3.
OBJECTIVE
To assess the frequency of consanguinity in b-thalassemia major patients and its association with age, gender and hepatitis C virus antibody positivity.
METHODS
The cross-sectional study was conducted from June 2013 to July 2014 at various hospitals of district Bannu in the North Western Khyber Pakhtunkhwa province of Pakistan. Data was recorded on a predesigned questionnaire.
RESULTS
Out of 180 subjects, 133(74%) parents were cousins, while 47(26%) were unrelated. The frequency of anti-hepatitis C virus antibody positivity was 14(7.77%).
CONCLUSIONS
High prevalence of the disease in the study region was due to consanguineous marriages.
目的
评估重型β地中海贫血患者的近亲结婚频率及其与年龄、性别和丙型肝炎病毒抗体阳性的关联。
方法
2013年6月至2014年7月在巴基斯坦开伯尔-普赫图赫瓦省西北部班努地区的多家医院进行了横断面研究。数据记录在预先设计的问卷上。
结果
在180名受试者中，133名（74%）的父母是近亲，而47名（26%）父母无血缘关系。抗丙型肝炎病毒抗体阳性率为14名（7.77%）。
结论
研究地区该疾病的高患病率归因于近亲结婚。
Zotero 插件