Alper O M, Erengin H, Manguoğlu A E, Bilgen T, Cetin Z, Dedeoğlu N, Lüleci G
Department of Medical Genetics, School of Medicine, Akdeniz University, Antalya 07070, Turkey.
Ann Genet. 2004 Apr-Jun;47(2):129-38. doi: 10.1016/j.anngen.2003.09.001.
To assess the trends in the frequency and the medical effects of consanguinity in the south coast of Turkish population using local and national data in the last 11 years. This cross-sectional study was carried out in Manavgat province, which is a major tourism center on the Mediterranean coast of Turkey. The authors studied consanguineous marriages in rural and urban population in the Mediterranean coast, Manavgat province, Turkey, via a 1500 random survey sample of married couples. There has been a significant increase in the incidence of consanguineous marriages in rural areas (40.7%) since 1989 in the southern population of Turkey. The results showed that the most frequent type of marriage was between the first cousins. It is found that there is no statistically significant difference between the consanguineous and non-consanguineous marriages in the different age groups. The results were discussed on the basis of educational status, reasons for having consanguineous marriages and the general medical effects as well as with the relation of congenital malformations. The custom of consanguineous unions in the Mediterranean population of Turkey is still extremely high, and preventive measures should be done to decrease its frequency and associated complications.
利用过去11年的当地和全国数据,评估土耳其南部沿海地区近亲结婚的频率趋势及其医学影响。这项横断面研究在土耳其地中海沿岸的主要旅游中心马纳夫加特省开展。作者通过对1500对已婚夫妇的随机抽样调查,研究了土耳其马纳夫加特省地中海沿岸农村和城市人口中的近亲婚姻情况。自1989年以来,土耳其南部农村地区近亲结婚率显著上升(40.7%)。结果显示,最常见的婚姻类型是表亲之间的婚姻。研究发现,不同年龄组的近亲婚姻和非近亲婚姻之间没有统计学上的显著差异。基于教育状况、近亲结婚原因、一般医学影响以及与先天性畸形的关系对结果进行了讨论。土耳其地中海地区近亲结合的习俗仍然极高,并应采取预防措施以降低其频率及相关并发症。