Masel E K, Berghoff A S, Schur S, Maehr B, Schrank B, Simanek R, Preusser M, Marosi C, Watzke H H
Clinical Division of Palliative Care, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.
Clinical Division of Oncology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.
Eur J Cancer Care (Engl). 2016 Jul;25(4):544-50. doi: 10.1111/ecc.12419. Epub 2015 Nov 12.
The comprehensive assessment of symptoms is the basis for effective, individualised palliative treatment. Established scoring systems provide in-depth information but are often lengthy and hence unsuitable. We introduce the PERS(2) ON score as a short and practically feasible score to evaluate symptom burden. Fifty patients admitted to a Palliative Care Unit rated seven items, i.e. pain, eating (loss of appetite/weight loss), rehabilitation (physical impairment), social situation (possibility for home care), suffering (anxiety/burden of disease/depression), O2 (dyspnoea) and nausea/emesis, on a scale ranging from 0 (absence) to 10 (worst imaginable), resulting in a score ranging from 0 to 70. Assessments were performed at admission, 7 days after admission and at the day of discharge. Symptom intensity scores were calculated, and change over time was evaluated. A significant improvement was observed from the PERS²ON score between admission and 7 days (P < 0.001; paired t-test). Significant improvement from baseline evaluation to evaluation on the day of discharge was observed (P = 0.001; paired t-test). This study provides initial evidence that the PERS²ON score is both feasible and sensitive to changes of the most prominent symptoms in palliative care. It may be useful in clinical practice to direct palliative treatment strategies and provide targeted symptom management.
症状的综合评估是有效、个体化姑息治疗的基础。既定的评分系统能提供深入信息，但往往冗长，因此并不适用。我们引入PERS(2)ON评分作为一种简短且切实可行的评分，用于评估症状负担。五十名入住姑息治疗病房的患者对疼痛、进食（食欲不振/体重减轻）、康复（身体损伤）、社会状况（家庭护理可能性）、痛苦（焦虑/疾病负担/抑郁）、氧气（呼吸困难）和恶心/呕吐这七个项目进行评分，评分范围为0（无）至10（难以想象的严重程度），最终得分范围为0至70分。在入院时、入院7天后及出院当天进行评估。计算症状强度得分，并评估随时间的变化。入院时与7天后的PERS²ON评分有显著改善（P < 0.001；配对t检验）。从基线评估到出院当天的评估有显著改善（P = 0.001；配对t检验）。本研究提供了初步证据，表明PERS²ON评分在姑息治疗中对最突出症状的变化既可行又敏感。它可能在临床实践中有助于指导姑息治疗策略并提供有针对性的症状管理。
