Çeviker Kadir, Şahinalp Şahin, Çiçek Erdinç, Demir Deniz, Uysal Dinçer, Yazkan Rasih, Akpınar Abdullah, Yavuz Turhan
Departments of Cardiovascular Surgery, Süleyman Demirel University, School of Medicine, Isparta, Turkey.
Kalp Damar Cerrahisi Anabilim Dalı, Tıp Fakültesi, Süleyman Demirel Üniversitesi, Isparta, Turkey.
Qual Life Res. 2016 Jun;25(6):1527-36. doi: 10.1007/s11136-015-1180-7. Epub 2015 Nov 13.
The main purpose of this study was to evaluate the influence of any of the four domains of the QoL score in CVD patients of classes C0-C4 and to analyze the correlation between the QoL and types of treatment modalities, and an additional aim of the present study was to compare QoL levels of patients with CVD and healthy participants and was to examine the factors associated with QoL in CVD patients.
The sample was composed of 501 patients with primary superficial venous reflux (28.5 % male and 71.5 % female) who answered 100 % of the questions in the World Health Organization Quality of Life (WHOQoL-BREF) questionnaire. After a clinical and duplex examination, the patients were categorized as C0-C4, according to the CEAP classification. The relationships between WHOQoL-BREF domains and gender, age, occupation, BMI, the clinical classes of the CEAP classification and four different treatment modalities according to guideline were analyzed.
For the WHOQOL-BREF test battery, the patients with CVD had worse values, as compared with the control group participants. The differences were significant for the physical (77.81 ± 12.75 vs. 59.18 ± 12.90, p < 0.001), the psychological (74.78 ± 11.37 vs. 60.21 ± 14.70, p < 0.001), the social relationships (76.56 ± 13.56 vs. 63.07 ± 21.37, p < 0.001) and the environmental (70.27 ± 13.36 vs. 50.16 ± 11.39, p < 0.001) health scores. The patients with CVD had worse WHOQOL-BREF scores at initial, compared with the 6-month follow-up scores.
This study shows that in spite of undergoing therapy, the subsequent QoL scores did not improve significantly, indicating that CVD continued to negatively affect the patient's life.
本研究的主要目的是评估生活质量（QoL）评分的四个领域中的任何一个对C0 - C4级心血管疾病（CVD）患者的影响，并分析生活质量与治疗方式类型之间的相关性。本研究的另一个目的是比较CVD患者与健康参与者的生活质量水平，并研究与CVD患者生活质量相关的因素。
样本由501例原发性浅静脉反流患者组成（男性占28.5%，女性占71.5%），他们100%回答了世界卫生组织生活质量（WHOQoL - BREF）问卷中的问题。经过临床和双功超声检查后，根据CEAP分类将患者分为C0 - C4级。分析了WHOQoL - BREF领域与性别、年龄、职业、体重指数（BMI）、CEAP分类的临床分级以及根据指南的四种不同治疗方式之间的关系。
对于WHOQOL - BREF测试组，与对照组参与者相比，CVD患者的得分更低。在生理（77.81±12.75对59.18±12.90，p<0.001）、心理（74.78±11.37对60.21±14.70，p<0.001）、社会关系（76.56±13.56对63.07±21.37，p<0.001）和环境（70.27±13.36对50.16±11.39，p<0.001）健康评分方面差异显著。与6个月随访评分相比，CVD患者初始时的WHOQOL - BREF评分更差。
本研究表明，尽管接受了治疗，但随后的生活质量评分并未显著改善，这表明CVD继续对患者生活产生负面影响。
