Transcription through Polycomb response elements does not induce a switch from repression to activation.
作者信息
Kassis Judith A, Müller Jürg
机构信息
Section on Gene Expression, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892;
Laboratory of Chromatin Biology, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.
出版信息
Proc Natl Acad Sci U S A. 2015 Dec 1;112(48):14755-6. doi: 10.1073/pnas.1520102112. Epub 2015 Nov 13.
Abstract
摘要
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Transcriptional read-through is not sufficient to induce an epigenetic switch in the silencing activity of Polycomb response elements.转录通读不足以在多梳反应元件的沉默活性中诱导表观遗传开关。
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