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Dabigatran and apolipoprotein B.

作者信息

ten Cate Hugo

出版信息

Heart. 2016 Jan;102(1):5-6. doi: 10.1136/heartjnl-2015-308575. Epub 2015 Nov 13.

DOI:10.1136/heartjnl-2015-308575
PMID:26567229
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4717405/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e81d/4717405/21575649e7bc/heartjnl-2015-308575f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e81d/4717405/21575649e7bc/heartjnl-2015-308575f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e81d/4717405/21575649e7bc/heartjnl-2015-308575f01.jpg

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本文引用的文献

1
Dabigatran etexilate and reduction in serum apolipoprotein B.达比加群酯与血清载脂蛋白B降低
Heart. 2016 Jan;102(1):57-62. doi: 10.1136/heartjnl-2015-307586. Epub 2015 Nov 9.
2
Differential cellular effects of old and new oral anticoagulants: consequences to the genesis and progression of atherosclerosis.新型与传统口服抗凝剂的细胞效应差异：对动脉粥样硬化发生与进展的影响
Thromb Haemost. 2014 Nov;112(5):909-17. doi: 10.1160/TH14-03-0268. Epub 2014 Oct 9.
3
Thrombin inhibition by dabigatran attenuates atherosclerosis in ApoE deficient mice.
达比加群和利伐沙班对多形核白细胞活化标志物的影响。
Pharmaceuticals (Basel). 2018 May 14;11(2):46. doi: 10.3390/ph11020046.
达比加群酯抑制凝血酶可减轻载脂蛋白 E 缺陷小鼠的动脉粥样硬化。
Arch Med Sci. 2014 Feb 24;10(1):154-60. doi: 10.5114/aoms.2014.40742. Epub 2014 Feb 23.
4
New insights into modulation of thrombin formation.对凝血酶形成的调节作用的新认识。
Curr Atheroscler Rep. 2013 Nov;15(11):363. doi: 10.1007/s11883-013-0363-3.
5
Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent manner.载脂蛋白 E 缺陷小鼠凝血酶形成的遗传和药理学修饰以中性粒细胞依赖的方式决定动脉粥样硬化的严重程度和动脉血栓形成的发生。
PLoS One. 2013;8(2):e55784. doi: 10.1371/journal.pone.0055784. Epub 2013 Feb 7.
6
The beneficial effects of a direct thrombin inhibitor, dabigatran etexilate, on the development and stability of atherosclerotic lesions in apolipoprotein E-deficient mice : dabigatran etexilate and atherosclerosis.直接凝血酶抑制剂达比加群酯对载脂蛋白 E 缺陷小鼠动脉粥样硬化病变的发展和稳定性的有益作用：达比加群酯与动脉粥样硬化。
Cardiovasc Drugs Ther. 2012 Oct;26(5):367-74. doi: 10.1007/s10557-012-6411-3.
7
The effects of direct thrombin inhibition with dabigatran on plaque formation and endothelial function in apolipoprotein E-deficient mice.达比加群酯对载脂蛋白 E 缺陷小鼠斑块形成和内皮功能的直接凝血酶抑制作用。
J Pharmacol Exp Ther. 2012 Nov;343(2):253-7. doi: 10.1124/jpet.112.194837. Epub 2012 Jul 25.
8
Dabigatran versus warfarin in patients with atrial fibrillation.达比加群与华法林用于房颤患者的比较。
N Engl J Med. 2009 Sep 17;361(12):1139-51. doi: 10.1056/NEJMoa0905561. Epub 2009 Aug 30.