秀丽隐杆线虫生物元素的高分辨率互补化学成像
High-resolution complementary chemical imaging of bio-elements in Caenorhabditis elegans.
作者信息
Hare Dominic J, Jones Michael W M, Wimmer Verena C, Jenkins Nicole L, de Jonge Martin D, Bush Ashley I, McColl Gawain
机构信息
Elemental Bio-imaging Facility, University of Technology Sydney, Broadway, New South Wales 2007, Australia and The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria 3010, Australia.
Australian Synchrotron, Clayton, Victoria 3168, Australia and ARC Centre of Excellence in Advanced Molecular Imaging, La Trobe Institute for Molecular Sciences, La Trobe University, Melbourne, 3086, Australia.
出版信息
Metallomics. 2016 Feb;8(2):156-60. doi: 10.1039/c5mt00288e.
Here, we present a sub-μm multimodal approach to image essential elements in Caenorhabditis elegans. A combination of chemical imaging technologies reveals total metal concentration, chemical state and the protein to which an element is associated. This application of distinct yet complementary chemical imaging techniques provided unique insight into essential and trace elements at the subcellular level.
在此，我们展示了一种用于对线虫体内基本元素进行成像的亚微米多模态方法。化学成像技术的组合揭示了总金属浓度、化学状态以及元素所关联的蛋白质。这种独特且互补的化学成像技术的应用在亚细胞水平上为必需元素和微量元素提供了独特的见解。
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