Hagiya Hideharu, Ogawa Hiroko, Takahashi Yusuke, Yamamoto Akira, Otsuka Fumio
Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan.
Intern Med. 2015;54(22):2939-41. doi: 10.2169/internalmedicine.54.4965. Epub 2015 Nov 15.
We herein report a case of Klebsiella oxytoca-producing IMP-1 that was detected as a first isolate of carbapenem-resistant Enterobacteriaceae (CRE) at our facility. Since K. oxytoca is an uncommon strain for CRE, we speculated that the resistant organism had already spread out inside the hospital. Metallo-β-lactamases promotes antibiotic resistance in Enterobacteriaceae, which potentially yields problematic issues in clinical settings. Active surveillance of antibiotic resistant strains is important and should be repeatedly highlighted. Furthermore, appropriate methods should be established to detect highly resistant strains.
我们在此报告1例产IMP-1的产酸克雷伯菌病例，该菌株在我们机构被检测为耐碳青霉烯类肠杆菌科细菌（CRE）的首例分离株。由于产酸克雷伯菌是CRE中不常见的菌株，我们推测这种耐药菌已在医院内传播。金属β-内酰胺酶可促进肠杆菌科细菌的抗生素耐药性，这在临床环境中可能会引发问题。对抗生素耐药菌株进行主动监测很重要，且应反复强调。此外，应建立适当的方法来检测高度耐药菌株。
