Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), No. 11 Beiyitiao, Zhongguancun, Beijing, 100190, China.
Key Lab for Green Chemical Process of Ministry of Education, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, 693 Xiongchu Ave, Wuhan, 430073, China.
Adv Mater. 2016 Jan 13;28(2):254-62. doi: 10.1002/adma.201503437. Epub 2015 Nov 16.
A pyropheophorbide-α-based building block (Ppa-PLGVRG-Van) can be used to construct self-aggregated superstructures in vivo for highly specific and sensitive diagnosis of bacterial infection by noninvasive photoacoustic tomography. This in vivo supramolecular chemistry approach opens a new avenue for efficient, rapid, and early-stage disease diagnosis with high sensitivity and specificity.
基于原卟啉 IX 的砌块（Ppa-PLGVRG-Van）可用于在体内构建自聚集超结构，通过非侵入性光声断层扫描对细菌感染进行高度特异性和灵敏的诊断。这种体内超分子化学方法为高效、快速和早期疾病诊断提供了新途径，具有高灵敏度和特异性。
