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一名男孩患模仿肉芽肿性唇炎的皮肤利什曼病,口服氟康唑成功治愈。

Cutaneous leishmaniasis mimicking granulomatous cheilitis and treated successfully with oral fluconazole in a boy.

作者信息

Serarslan Gamze, Aksakal Metin

机构信息

Department of Dermatology, Faculty of Medicine, Mustafa Kemal University, İskenderun St., Hatay 31100, Turkey.

出版信息

Ann Parasitol. 2015;61(3):197-9. doi: 10.17420/ap6103.08.

DOI:10.17420/ap6103.08
PMID:26568994
Abstract

Cutaneous leishmaniasis is a protozoan infectious disease and widespread in Mediterranean basin including Turkey. Lesions usually start with erythematous papules, gradually enlarges and afterwards it ulcerates. We present a 12-year-old boy with diffuse persistent lip swelling mimicking granulomatous cheilitis. Systemic glucantime was started. However, severe hypotension and bradycardia was developed after injection. Oral fluconazole was started and the lesion resolved completely. Cutaneous leishmaniasis can have varied clinical manifestations and should be suspected especially in endemic areas. Oral fluconazole seems to be safe and effective treatment modality in paediatric cases.

摘要

皮肤利什曼病是一种原生动物传染病,在地中海盆地包括土耳其广泛流行。病变通常始于红斑丘疹,逐渐扩大,随后溃疡。我们报告一名12岁男孩,表现为弥漫性持续性唇部肿胀,类似肉芽肿性唇炎。开始使用全身性葡糖胺锑。然而,注射后出现严重低血压和心动过缓。开始口服氟康唑,病变完全消退。皮肤利什曼病可有多种临床表现,尤其在流行地区应予以怀疑。口服氟康唑在儿科病例中似乎是一种安全有效的治疗方式。

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