Baldinger Samuel H, Stevenson William G, John Roy M
Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Curr Opin Cardiol. 2016 Jan;31(1):29-36. doi: 10.1097/HCO.0000000000000237.
This article summarizes current understanding of the arrhythmia substrate and effect of catheter ablation for infarct-related ventricular tachycardia, focusing on recent findings.
Clinical studies support the use of catheter ablation earlier in the course of ischemic disease with moderate success in reducing arrhythmia recurrence and shocks from implantable defibrillators, although mortality remains unchanged. Ablation can be lifesaving for patients presenting with electrical storm. Advanced mapping systems with image integration facilitate identification of potential substrate, and several different approaches to manage hemodynamically unstable ventricular tachycardia have emerged. Novel ablation techniques that allow deeper lesion formation are in development.
Catheter ablation is an important therapeutic option for preventing or reducing episodes of ventricular tachycardia in patients with ischemic cardiomyopathy. Present technologies allow successful ablation in the majority of patients, even when the arrhythmia is hemodynamically unstable. Failure of the procedure is often because of anatomic challenges that will hopefully be addressed with technological progress.
本文总结了目前对梗死相关室性心动过速的心律失常基质及导管消融效果的认识,重点关注近期研究结果。
临床研究支持在缺血性疾病进程中更早地使用导管消融,在减少心律失常复发及植入式除颤器电击方面取得了一定成功,尽管死亡率未变。消融对出现电风暴的患者可挽救生命。具有图像整合功能的先进标测系统有助于识别潜在基质,并且出现了几种不同的处理血流动力学不稳定室性心动过速的方法。能形成更深损伤的新型消融技术正在研发中。
导管消融是预防或减少缺血性心肌病患者室性心动过速发作的重要治疗选择。现有技术能使大多数患者成功消融,即使心律失常是血流动力学不稳定的。手术失败通常是由于解剖学上的挑战,有望随着技术进步得到解决。