Campos-Magdaleno María, Díaz-Bóveda Rosalía, Juncos-Rabadán Onésimo, Facal David, Pereiro Arturo X
a Department of Developmental and Educational Psychology , University of Santiago de Compostela , Santiago de Compostela , Spain.
Appl Neuropsychol Adult. 2016 Jul-Aug;23(4):237-50. doi: 10.1080/23279095.2015.1053887. Epub 2015 Nov 16.
The objective of this study was to examine different patterns of learning and episodic memory in 3 mild cognitive impairment (MCI) groups and a control group by administering the California Verbal Learning Test (CVLT) and using serial position effect as a principal variable. The study sample included 3 groups of patients with MCI (n = 90) divided into single-domain amnestic, multiple-domain amnestic, and multiple-domain nonamnestic MCI and a group of healthy controls (n = 60). We compared the performance of each group on several CVLT measures used in previous research, and we included a new measure that provides specific information about the serial effect. Data showed a similar pattern of learning and memory impairment in both amnestic MCI groups (i.e., no differences between the multiple-domain and single-domain subtypes); the recency effect was significantly higher in both amnestic MCI groups than in all other groups, and the primacy effect was only lower in the multiple-domain amnestic MCI subtype. Verbal learning and memory profiles of patients with amnestic MCI were very similar, independent of the presence of deficits in cognitive domains other than episodic memory. Results are discussed in light of the unitary-store model of memory.
本研究的目的是通过实施加利福尼亚言语学习测验（CVLT）并将系列位置效应作为主要变量，来考察3个轻度认知障碍（MCI）组和1个对照组的不同学习模式和情景记忆。研究样本包括3组MCI患者（n = 90），分为单领域遗忘型、多领域遗忘型和多领域非遗忘型MCI，以及1组健康对照组（n = 60）。我们比较了每组在先前研究中使用的几种CVLT测量指标上的表现，并且纳入了一项能提供有关系列效应具体信息的新指标。数据显示，两个遗忘型MCI组的学习和记忆损害模式相似（即多领域和单领域亚型之间无差异）；两个遗忘型MCI组的近因效应均显著高于所有其他组，且首因效应仅在多领域遗忘型MCI亚型中较低。遗忘型MCI患者的言语学习和记忆概况非常相似，与情景记忆以外的认知领域是否存在缺陷无关。我们根据记忆的单一存储模型对结果进行了讨论。
