Schwindl B, Bschleipfer T, Klotz T
Klinik für Urologie, Andrologie und Kinderurologie, Klinikum Weiden/Kliniken Nordoberpfalz AG, Söllnerstr. 16, 92637, Weiden, Deutschland.
Urologe A. 2015 Nov;54(11):1631-9; quiz 1640-1. doi: 10.1007/s00120-015-3987-9.
Priapism is characterized by involuntary persistent penile erection after or independent of sexual stimulation. The diagnostic clarification, including patient history, physical findings, duplex ultrasonography and analysis of blood gases is decisive for the underlying pathophysiology and the appropriate therapeutic procedure. Non-hypoxic and non-acidotic blood gas parameters enable a conservative approach, hypoxic, hypercarbic and acidotic parameters may lead to fibrosis of the corpora cavernosa and, in turn, to a loss of penile function. Low-flow or ischemic (veno-occlusive) priapism is an emergency situation and can lead to irreversible erectile dysfunction within 4 h. Treatment consists of blood aspiration and possibly intracavernosal injection of sympathomimetic drugs. A distal shunt is necessary in the case of treatment failure (in rare cases a proximal shunt). Management of recurrent priapism (stuttering) includes self-injection of sympathomimetic drugs and preventive long-term administration of erection inhibitory and erection promoting substances. This concept still needs to be validated. High-flow or non-ischemic priapism does not necessitate immediate treatment measures and should be kept under observation. In cases of a detectable fistula selective artery embolization is often a successful option.
阴茎异常勃起的特征是在性刺激之后或与之无关的情况下,阴茎出现不自主的持续性勃起。诊断的明确,包括患者病史、体格检查结果、双功超声检查以及血气分析,对于潜在的病理生理学和恰当的治疗程序具有决定性意义。非低氧和非酸中毒的血气参数支持采取保守治疗方法,而低氧、高碳酸血症和酸中毒的参数可能导致海绵体纤维化,进而导致阴茎功能丧失。低流量或缺血性(静脉闭塞性)阴茎异常勃起是一种紧急情况,可在4小时内导致不可逆的勃起功能障碍。治疗方法包括抽血,可能还需要海绵体内注射拟交感神经药物。治疗失败时(罕见情况下采用近端分流)需要进行远端分流。复发性阴茎异常勃起(间歇性)的管理包括自我注射拟交感神经药物以及长期预防性使用勃起抑制和促进勃起的物质。这一概念仍需验证。高流量或非缺血性阴茎异常勃起无需立即采取治疗措施,应予以观察。在可检测到瘘管的情况下,选择性动脉栓塞通常是一种成功的选择。