O'Regan S, Melhorn D K, Newman A J, Graham R C
Can Med Assoc J. 1977 May 7;116(9):1029-30.
A 5-year illness of a child, characterized by recurrent bacterial infections and abnormal results of nitroblue tetrazolium dye reduction tests, was suggestive of chronic granulomatous disease but the illness terminated in overt myeloid leukemia. During this progression studies of leukocyte structure and metabolic activity revealed abnormalities that suggested the existence of a "preleukemic" state.
一名儿童患有一种持续5年的疾病，其特征为反复发生细菌感染以及硝基四氮唑蓝染料还原试验结果异常，提示为慢性肉芽肿病，但该疾病最终发展为明显的髓系白血病。在这一病程中，对白细胞结构和代谢活性的研究揭示了一些异常情况，提示存在“白血病前期”状态。
