Adcock L L, Downey G O, Votel J L
Department of Obstetrics and Gynecology, University of Minnesota Medical School, Minneapolis.
Obstet Gynecol Surv. 1989 May;44(5):347-54. doi: 10.1097/00006254-198905000-00012.
Fibromatosis is a benign, infiltrating, nonmetastasizing neoplasm which is rarely completely resected. Therefore, the incidence of recurrence is high. Fibromatosis is more common in females and is frequently diagnosed during pregnancy. Inasmuch as fibromatosis of the female pelvis appears to be a discrete entity, management poses significant problems for the gynecologist. Radiation therapy, frequently used following incomplete resection or for recurrence, is undesirable due to the loss of ovarian function and fertility. Hormonal manipulation and combination chemotherapy are alternatives which have been effective in some reports. Three patients with pelvic fibromatosis, referred within 1 year, are reported. The various aspects of this neoplasm and the diagnostic procedures are discussed. Treatment modalities whose effects are reversible are recommended for recurrent fibromatosis. Radiation therapy can be reserved for patients in the older age groups or for those with progressive disease not responding to other therapy.
纤维瘤病是一种良性、浸润性、不发生转移的肿瘤，很少能完全切除。因此，复发率很高。纤维瘤病在女性中更为常见，且常在孕期被诊断出来。鉴于女性盆腔纤维瘤病似乎是一种独立的疾病，其治疗给妇科医生带来了重大难题。放射治疗常在不完全切除后或复发时使用，但由于卵巢功能和生育能力丧失，这种治疗方法并不理想。激素治疗和联合化疗是在一些报告中有效的替代方法。本文报告了3例在1年内转诊的盆腔纤维瘤病患者。讨论了该肿瘤的各个方面及诊断程序。对于复发性纤维瘤病，建议采用效果可逆的治疗方式。放射治疗可保留给老年患者或对其他治疗无反应的进展性疾病患者。
