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他莫昔芬用于复发性胸壁硬纤维瘤。

Tamoxifen for recurrent desmoid tumor of the chest wall.

作者信息

Ohashi Toshio, Shigematsu Naoyuki, Kameyama Kaori, Kubo Atsushi

机构信息

Department of Radiology, School of Medicine, Keio University, 35 Shinanomachi, Tokyo 160-8582, Japan.

出版信息

Int J Clin Oncol. 2006 Apr;11(2):150-2. doi: 10.1007/s10147-005-0543-4.

DOI:10.1007/s10147-005-0543-4
PMID:16622751
Abstract

We report a case of a young woman with recurrent desmoid tumor. Computed tomography (CT) scans of the chest showed a large mass in the left chest wall. The tumor was unresectable because of the involvement of adjacent structures. Tamoxifen therapy led to marked tumor regression within 3 months. She had preserved her fertility, and thereafter she conceived a baby. In young women with recurrent desmoid tumor, tamoxifen should be considered as the first choice of treatment.

摘要

我们报告一例患有复发性硬纤维瘤的年轻女性病例。胸部计算机断层扫描(CT)显示左胸壁有一个大肿块。由于邻近结构受累,该肿瘤无法切除。他莫昔芬治疗在3个月内导致肿瘤明显消退。她保留了生育能力,此后怀孕并生下一个婴儿。对于患有复发性硬纤维瘤的年轻女性,应考虑将他莫昔芬作为首选治疗方法。

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本文引用的文献

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三苯氧胺对猪胆总管吻合口纤维化、胶原含量及转化生长因子-β1、β2、β3 表达的影响。
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[Retroperitoneal desmoid tumor].[腹膜后硬纤维瘤]
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[Desmoid tumor of the thoracic wall].[胸壁硬纤维瘤]
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