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用于分析氧化石墨烯纳米结构中集成的氧化锌纳米棒抗菌效果的基质辅助激光解吸电离质谱分析、纸片扩散法和光密度测量。

MALDI MS analysis, disk diffusion and optical density measurements for the antimicrobial effect of zinc oxide nanorods integrated in graphene oxide nanostructures.

作者信息

Bhaisare Mukesh Lavkush, Wu Bo-Sgum, Wu Mon-Chun, Khan M Shahnawaz, Tseng Mei-Hwei, Wu Hui-Fen

机构信息

Department of Chemistry, National Sun Yat-Sen University, Kaohsiung, 80424, Taiwan.

Department of Applied Physics and Chemistry, University of Taipei, Taipei, 10048, Taiwan.

出版信息

Biomater Sci. 2016 Jan;4(1):183-94. doi: 10.1039/c5bm00342c.

DOI:10.1039/c5bm00342c
PMID:26575840
Abstract

Graphene oxide-zinc oxide hybrid nanostructures were synthesized and they demonstrated significant and promising antimicrobial activity on pathogenic bacteria. The combination of graphene oxide with zinc oxide nanorods showed an impressive antibacterial effect under intense scrutiny as compared with individual graphene oxide or zinc oxide nanomaterials. The characterization and investigation of GO-ZnO nanorod hybrid nanostructures were conducted using UV, FTIR, XRD, SEM, EDX and TEM measurements. The antimicrobial activity of the above hybrid material was evaluated by various methods including MALDI-MS analysis, a disk diffusion assay and optical density measurements.

摘要

合成了氧化石墨烯-氧化锌混合纳米结构,它们对病原菌表现出显著且有前景的抗菌活性。与单独的氧化石墨烯或氧化锌纳米材料相比,氧化石墨烯与氧化锌纳米棒的组合在严格审查下显示出令人印象深刻的抗菌效果。使用紫外、傅里叶变换红外光谱、X射线衍射、扫描电子显微镜、能谱分析和透射电子显微镜测量对氧化石墨烯-氧化锌纳米棒混合纳米结构进行了表征和研究。通过包括基质辅助激光解吸电离质谱分析、纸片扩散法和光密度测量在内的各种方法评估了上述混合材料的抗菌活性。

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