Parthenogenetic haploid embryonic stem cells efficiently support mouse generation by oocyte injection.
作者信息
Zhong Cuiqing, Xie Zhenfei, Yin Qi, Dong Rui, Yang Suming, Wu Yuxuan, Yang Li, Li Jinsong
机构信息
Group of Epigenetic Reprogramming, State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Shanghai Key Laboratory of Molecular Andrology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
出版信息
Cell Res. 2016 Jan;26(1):131-4. doi: 10.1038/cr.2015.132. Epub 2015 Nov 17.
Abstract
摘要
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CRISPR-Cas9-Mediated Genetic Screening in Mice with Haploid Embryonic Stem Cells Carrying a Guide RNA Library.利用携带向导 RNA 文库的单倍体胚胎干细胞进行 CRISPR-Cas9 介导的基因筛选。
Cell Stem Cell. 2015 Aug 6;17(2):221-32. doi: 10.1016/j.stem.2015.06.005. Epub 2015 Jul 9.
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Annu Rev Cell Dev Biol. 2014;30:705-22. doi: 10.1146/annurev-cellbio-100913-012920.
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Parthenogenetic haploid embryonic stem cells produce fertile mice.孤雌生殖单倍体胚胎干细胞可产生可育小鼠。
Cell Res. 2013 Nov;23(11):1330-3. doi: 10.1038/cr.2013.126. Epub 2013 Sep 10.
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Generation of haploid embryonic stem cells from Macaca fascicularis monkey parthenotes.从食蟹猴孤雌胚胎中生成单倍体胚胎干细胞。
Cell Res. 2013 Oct;23(10):1187-200. doi: 10.1038/cr.2013.93. Epub 2013 Jul 16.
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Haploid embryonic stem cells: an ideal tool for mammalian genetic analyses.单倍体胚胎干细胞：哺乳动物遗传分析的理想工具。
Protein Cell. 2012 Nov;3(11):806-10. doi: 10.1007/s13238-012-2096-4. Epub 2012 Sep 28.
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Androgenetic haploid embryonic stem cells produce live transgenic mice.雄原单倍体胚胎干细胞可产生活体转基因小鼠。
Nature. 2012 Oct 18;490(7420):407-11. doi: 10.1038/nature11435. Epub 2012 Sep 30.
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Generation of genetically modified mice by oocyte injection of androgenetic haploid embryonic stem cells.通过卵母细胞注射雄核单倍体胚胎干细胞生成基因修饰小鼠。
Cell. 2012 Apr 27;149(3):605-17. doi: 10.1016/j.cell.2012.04.002.
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Forward and reverse genetics through derivation of haploid mouse embryonic stem cells.通过诱导单倍体胚胎干细胞进行正向和反向遗传学研究。
Cell Stem Cell. 2011 Dec 2;9(6):563-74. doi: 10.1016/j.stem.2011.10.012.
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Derivation of haploid embryonic stem cells from mouse embryos.从老鼠胚胎中提取单倍体胚胎干细胞。
Nature. 2011 Sep 7;479(7371):131-4. doi: 10.1038/nature10448.
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The ground state of embryonic stem cell self-renewal.胚胎干细胞自我更新的基态。
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