Fritz Nora E, Jiang Allen, Keller Jennifer, Zackowski Kathleen M
Kennedy Krieger Institute, Motion Analysis Laboratory, Baltimore, MD; Department of Physical Medicine and Rehabilitation, Johns Hopkins School of Medicine, Baltimore, MD.
Kennedy Krieger Institute, Motion Analysis Laboratory, Baltimore, MD.
Arch Phys Med Rehabil. 2016 Apr;97(4):507-512. doi: 10.1016/j.apmr.2015.10.100. Epub 2015 Nov 11.
To examine the concurrent validity of the Six-Spot Step Test (SSST) with clinical measures of walking and spatiotemporal measures of gait in multiple sclerosis (MS), and to understand the utility of the SSST in individuals with both low and high levels of disability.
Cross-sectional study.
Laboratory.
Individuals with relapsing-remitting MS (N=29).
Not applicable.
In a single visit, demographic information (age, sex, Expanded Disability Status Scale [EDSS], symptom duration) and functional measures (SSST, timed Up and Go [TUG] test, timed 25-foot walk [T25FW] test, spatiotemporal measures of walking) were collected.
The SSST demonstrates concurrent validity with the TUG test, T25FW test, and 2-minute walk test (2MWT) (P≤.0002). Both spatial and temporal measures of gait are significantly related to SSST performance (P<.004). In individuals with lower disability (EDSS score 1-3.5), the SSST remains strongly related to the TUG test and T25FW test performances, whereas it fails to relate to any other measures. However, in the higher disability group (EDSS score 4-6), the SSST is significantly related to the TUG test, T25FW test, 2MWT, walk velocity, and both temporal and spatial measures of gait.
The SSST is an alternative test for lower-extremity function in the clinical setting that may useful in both higher and lower EDSS groups. The SSST requires minimal training to administer and may be a time-efficient measure of real-life functional performance that would be useful in large clinical trials.
探讨六点步阶试验（SSST）与多发性硬化症（MS）患者步行的临床测量指标及步态时空测量指标之间的同时效度，并了解SSST在低残疾水平和高残疾水平个体中的效用。
横断面研究。
实验室。
复发缓解型MS患者（N = 29）。
不适用。
在单次就诊时，收集人口统计学信息（年龄、性别、扩展残疾状态量表[EDSS]、症状持续时间）和功能测量指标（SSST、计时起立行走试验[TUG]、25英尺计时步行试验[T25FW]、步行的时空测量指标）。
SSST与TUG试验、T25FW试验及2分钟步行试验（2MWT）具有同时效度（P≤.0002）。步态的空间和时间测量指标均与SSST表现显著相关（P<.004）。在残疾程度较低（EDSS评分1 - 3.5）的个体中，SSST与TUG试验和T25FW试验表现仍密切相关，而与其他任何测量指标均无关联。然而，在高残疾组（EDSS评分4 - 6）中，SSST与TUG试验、T25FW试验、2MWT、步行速度以及步态的时间和空间测量指标均显著相关。
SSST是临床环境中用于评估下肢功能的一种替代试验，在EDSS评分较高和较低的组中可能均有用。SSST实施所需的培训极少，可能是一种衡量现实生活功能表现的高效省时指标，在大型临床试验中会很有用。
