Zuchero J Bradley, Barres Ben A
Department of Neurobiology, Stanford University, School of Medicine, Stanford, CA 94305, USA
Department of Neurobiology, Stanford University, School of Medicine, Stanford, CA 94305, USA.
Development. 2015 Nov 15;142(22):3805-9. doi: 10.1242/dev.129304.
Glia account for more than half of the cells in the mammalian nervous system, and the past few decades have witnessed a flood of studies that detail novel functions for glia in nervous system development, plasticity and disease. Here, and in the accompanying poster, we review the origins of glia and discuss their diverse roles during development, in the adult nervous system and in the context of disease.
神经胶质细胞占哺乳动物神经系统细胞的一半以上,在过去几十年里,涌现出大量研究,详细阐述了神经胶质细胞在神经系统发育、可塑性和疾病中的新功能。在此,以及在随附的海报中,我们回顾了神经胶质细胞的起源,并讨论了它们在发育过程中、成年神经系统以及疾病背景下的多种作用。