Ozdogan Sebnem, Tabakci Burcu, Demirel Ayse Sirin, Atli Bilge, Besli Gulser Esen, Kose Gulsen
Sisli Hamidiye Etfal Research and Training Hospital, Istanbul, Turkey.
Sinan Ercan Sok, Isiklar 1 Apt. No 34, Da: 23, 34742, Kozyataği, Istanbul, Turkey.
Ital J Pediatr. 2015 Nov 17;41:91. doi: 10.1186/s13052-015-0201-z.
We aimed to evaluate the risk factors in preschool children admitted to inpatient services with a diagnosis of recurrent attacks of wheezing.
The medical files of 44 preschool children with 2 or more recurrent hospitalizations resulting from wheezing between November 2011 and January 2012 were retrospectively investigated.
There were 28 males (64 %) and 16 females. The median age was 14 months (2.0-50). The median numbers of previous wheezing attacks and hospitalizations were 4 (2-10) and 2 (2-8), respectively. Fourteen patients (32 %) had been treated for gastroesophageal reflux (GER). The previous and recent hospital evaluations were investigated. Bronchopulmonary dysplasia and anemia were significantly more common in patients with 3 or more hospitalizations for wheezing than in those with 2 hospitalizations (p = 0.010 and p < 0.001, respectively). A review of the cases with 3 or more hospitalizations revealed that a history of GER and anemia were significant risk factors.
Anemia and GER are risk factors for recurrent hospitalizations resulting from wheezing and should be treated. If the history and physical examination suggest asthma, inhaler therapy treatment should be administered, with other investigations planned for patients who do not respond to treatment as expected.
我们旨在评估诊断为喘息反复发作而入住住院服务的学龄前儿童的风险因素。
回顾性调查了2011年11月至2012年1月期间因喘息而反复住院2次或更多次的44名学龄前儿童的病历。
男性28名（64%），女性16名。中位年龄为14个月（2.0 - 50）。既往喘息发作次数和住院次数的中位数分别为4次（2 - 10次）和2次（2 - 8次）。14名患者（32%）曾接受过胃食管反流（GER）治疗。对既往和近期的住院评估进行了调查。喘息住院3次或更多次的患者中，支气管肺发育不良和贫血明显比住院2次的患者更常见（分别为p = 0.010和p < 0.001）。对住院3次或更多次的病例进行回顾发现，GER病史和贫血是重要的风险因素。
贫血和GER是喘息导致反复住院的风险因素，应予以治疗。如果病史和体格检查提示哮喘，应给予吸入器治疗，对于对治疗无预期反应的患者应安排其他检查。
