Coping with cancer genes altered by copy number.
作者信息
Wolf Natalie K, Largaespada David A, Moriarity Branden S
机构信息
Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Twin Cities, MN, USA.
出版信息
Oncotarget. 2015 Nov 3;6(34):35155-6. doi: 10.18632/oncotarget.6215.
Abstract
摘要
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A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis.一项“睡美人”正向遗传学筛选鉴定出驱动骨肉瘤发生和转移的新基因及信号通路。
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Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis.正向遗传筛选致恶性外周神经鞘瘤形成，发现新基因和通路驱动肿瘤发生。
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