Lin Hui-Ting, Wang Ching-Ho, Chueh Ling-Ling, Su Bi-Ling, Wang Lih-Chiann
Emerg Infect Dis. 2015 Dec;21(12):2154-7. doi: 10.3201/eid2112.141229.
We determined the prevalence of influenza A virus in dogs in Taiwan and isolated A/canine/Taiwan/E01/2014. Molecular analysis indicated that this isolate was closely related to influenza A(H6N1) viruses circulating in Taiwan and harbored the E627K substitution in the polymerase basic 2 protein, which indicated its ability to replicate in mammalian species.
我们确定了台湾地区犬类甲型流感病毒的流行情况,并分离出A/犬/台湾/E01/2014毒株。分子分析表明,该分离株与在台湾地区传播的甲型流感病毒A(H6N1)密切相关,且在聚合酶碱性蛋白2中存在E627K替换,这表明其具有在哺乳动物物种中复制的能力。