[Spiramycin].

Chemotherapeutic agents appear to offer a great potential in the treatment of periodontal disease in conjunction with root planning and/or surgical approach. One of these chemotherapeutic agents is spiramycin. The aim of this paper is to review some data about the spiramycin in vitro, in vivo, the effects of spiramycin on plaque control and some interesting hypothesis on action of spiramycin.