Barona-Dorado Cristina, Gutierrez-Bonet Carmen, Leco-Berrocal Isabel, Fernández-Cáliz Fernando, Martínez-González José-María
Plaza Ramón y Cajal, s/n, 28040 Madrid, Spain,
Med Oral Patol Oral Cir Bucal. 2016 Jan 1;21(1):e66-71. doi: 10.4317/medoral.20183.
In recent years the use of orthopantomography has been proposed as a low-cost, reliable and non-invasive diagnostic medium for detecting atheromatous plaque. The purpose of this study was to correlate the presence of carotid calcifications (atheroma) in orthopantomographs with specific risk factors for cerebrovascular accidents (previous cerebrovascular accidents, arterial hypertension, and diabetes).
The methods used in this observational study of cases and control subjects followed STROBE (Strengthening the Reporting of Observational studies in Epidemiology) recommendations. The study analyzed a total of 1,602 panoramic radiographs taken for dental diagnostic purposes between January 2010 and February 2014. The main variables analyzed were the incidence of atheromatous plaque and other cardiovascular risk factors. Epidat 3.1 statistical software was used to determine minimum sample sizes and the results were analyzed using PASW (Predictive Analytics Software) Statistics 10.0.0.
For all the variables analyzed, the correlation between radiographic detection of atheromatous plaque and the presence of cardiovascular disease risk factors was found to be statistically significant (RR>1.5).
The presence of cardiovascular risk factors is related to the incidence of radiopaque lesions at the carotid artery bifurcation, indicating the presence of atheromatous plaque.
近年来,有人提出使用曲面断层摄影作为一种低成本、可靠且无创的诊断手段来检测动脉粥样硬化斑块。本研究的目的是将曲面断层片中颈动脉钙化(动脉粥样硬化)的存在情况与脑血管意外的特定危险因素(既往脑血管意外、动脉高血压和糖尿病)进行关联分析。
本病例对照观察性研究采用的方法遵循了STROBE(加强流行病学观察性研究报告)建议。该研究分析了2010年1月至2014年2月期间为牙科诊断目的拍摄的总共1602张全景X线片。分析的主要变量是动脉粥样硬化斑块的发生率和其他心血管危险因素。使用Epidat 3.1统计软件确定最小样本量,并使用PASW(预测分析软件)Statistics 10.0.0对结果进行分析。
对于所有分析的变量,发现动脉粥样硬化斑块的影像学检测与心血管疾病危险因素的存在之间的相关性具有统计学意义(RR>1.5)。
心血管危险因素的存在与颈动脉分叉处不透射线病变的发生率相关,表明存在动脉粥样硬化斑块。