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[铊-201 心肌灌注单光子发射计算机断层扫描研究中使用多焦点准直器系统进行散射和衰减校正的最佳重建参数]

[The Optimal Reconstruction Parameters by Scatter and Attenuation Corrections Using Multi-focus Collimator System in Thallium-201 Myocardial Perfusion SPECT Study].

作者信息

Shibutani Takayuki, Onoguchi Masahisa, Funayama Risa, Nakajima Kenichi, Matsuo Shinro, Yoneyama Hiroto, Konishi Takahiro, Kinuya Seigo

机构信息

Department of Quantum Medical Technology, Faculty of Health Sciences, Kanazawa University.

出版信息

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2015 Nov;71(11):1103-12. doi: 10.6009/jjrt.2015_JSRT_71.11.1103.

Abstract

The aim of this study was to reveal the optimal reconstruction parameters of ordered subset conjugates gradient minimizer (OSCGM) by no correction (NC), attenuation correction (AC), and AC+scatter correction (ACSC) using IQ-single photon emission computed tomography (SPECT) system in thallium-201 myocardial perfusion SPECT. Myocardial phantom acquired two patterns, with or without defect. Myocardial images were performed 5-point scale visual score and quantitative evaluations using contrast, uptake, and uniformity about the subset and update (subset×iteration) of OSCGM and the full width at half maximum (FWHM) of Gaussian filter by three corrections. We decided on optimal reconstruction parameters of OSCGM by three corrections. The number of subsets to create suitable images were 3 or 5 for NC and AC, 2 or 3 for ACSC. The updates to create suitable images were 30 or 40 for NC, 40 or 60 for AC, and 30 for ACSC. Furthermore, the FWHM of Gaussian filters were 9.6 mm or 12 mm for NC and ACSC, 7.2 mm or 9.6 mm for AC. In conclusion, the following optimal reconstruction parameters of OSCGM were decided; NC: subset 5, iteration 8 and FWHM 9.6 mm, AC: subset 5, iteration 8 and FWHM 7.2 mm, ACSC: subset 3, iteration 10 and FWHM 9.6 mm.

摘要

本研究的目的是通过无校正(NC)、衰减校正(AC)和AC+散射校正(ACSC),利用铊-201心肌灌注单光子发射计算机断层扫描(SPECT)系统中的IQ-单光子发射计算机断层扫描(SPECT)系统,揭示有序子集共轭梯度最小化器(OSCGM)的最佳重建参数。心肌模型获得了有缺陷和无缺陷两种模式。通过三种校正方法,对心肌图像进行5分制视觉评分,并使用关于OSCGM的子集和更新(子集×迭代)的对比度、摄取和均匀性以及高斯滤波器的半高宽(FWHM)进行定量评估。我们通过三种校正方法确定了OSCGM的最佳重建参数。对于NC和AC,创建合适图像的子集数量为3或5,对于ACSC为2或3。对于NC,创建合适图像的更新次数为30或40,对于AC为40或60,对于ACSC为30。此外,对于NC和ACSC,高斯滤波器的FWHM为9.6毫米或12毫米,对于AC为7.2毫米或9.6毫米。总之,确定了OSCGM的以下最佳重建参数;NC:子集5,迭代8,FWHM 9.6毫米;AC:子集5,迭代8,FWHM 7.2毫米;ACSC:子集3,迭代10,FWHM 9.6毫米。

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