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主动脉复苏性血管内球囊阻断术(REBOA):基于人群的英格兰和威尔士创伤患者差距分析。

Resuscitative endovascular balloon occlusion of the aorta (REBOA): a population based gap analysis of trauma patients in England and Wales.

作者信息

Barnard Edward Benjamin Graham, Morrison Jonathan James, Madureira Ricardo Mondoni, Lendrum Robbie, Fragoso-Iñiguez Marisol, Edwards Antoinette, Lecky Fiona, Bouamra Omar, Lawrence Thomas, Jansen Jan Olaf

机构信息

Institute of Naval Medicine, Gosport, Hampshire, UK Office of the Chief Scientist, 59th Medical Wing, Joint Base San Antonio, United States Air Force, San Antonio, Texas, USA.

Academic Department of Military Surgery and Trauma, Royal Centre for Defence Medicine, Birmingham, UK Academic Unit of Surgery, Glasgow Royal Infirmary, Glasgow, UK.

出版信息

Emerg Med J. 2015 Dec;32(12):926-32. doi: 10.1136/emermed-2015-205217.

Abstract

INTRODUCTION

Non-compressible torso haemorrhage (NCTH) carries a high mortality in trauma as many patients exsanguinate prior to definitive haemorrhage control. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an adjunct that has the potential to bridge patients to definitive haemostasis. However, the proportion of trauma patients in whom REBOA may be utilised is unknown.

METHODS

We conducted a population based analysis of 2012-2013 Trauma Audit and Research Network (TARN) data. We identified the number of patients in whom REBOA may have been utilised, defined by an Abbreviated Injury Scale score ≥3 to abdominal solid organs, abdominal or pelvic vasculature, pelvic fracture with ring disruption or proximal traumatic lower limb amputation, together with a systolic blood pressure <90 mm Hg. Patients with non-compressible haemorrhage in the mediastinum, axilla, face or neck were excluded.

RESULTS

During 2012-2013, 72 677 adult trauma patients admitted to hospitals in England and Wales were identified. 397 patients had an indication(s) and no contraindications for REBOA with evidence of haemorrhagic shock: 69% men, median age 43 years and median Injury Severity Score 32. Overall mortality was 32%. Major trauma centres (MTCs) received the highest concentration of potential REBOA patients, and would be anticipated to receive a patient in whom REBOA may be utilised every 95 days, increasing to every 46 days in the 10 MTCs with the highest attendance of this injury type.

CONCLUSIONS

This TARN database analysis has identified a small group of severely injured, resource intensive patients with a highly lethal injury that is theoretically amenable to REBOA. The highest density of these patients is seen at MTCs, and as such a planned evaluation of REBOA should be further considered in these hospitals.

摘要

引言

不可压缩性躯干出血(NCTH)在创伤中死亡率很高,因为许多患者在实现确定性出血控制之前就已失血过多。复苏性血管内主动脉球囊阻断术(REBOA)是一种辅助手段,有可能帮助患者实现确定性止血。然而,可使用REBOA的创伤患者比例尚不清楚。

方法

我们对2012 - 2013年创伤审计与研究网络(TARN)的数据进行了基于人群的分析。我们确定了可能使用REBOA的患者数量,其定义为腹部实体器官、腹部或盆腔血管、伴有骨盆环破坏的骨盆骨折或近端创伤性下肢截肢的简明损伤定级评分≥3,同时收缩压<90 mmHg。纵隔、腋窝、面部或颈部有不可压缩性出血的患者被排除。

结果

在2012 - 2013年期间,确定有72677名成年创伤患者入住英格兰和威尔士的医院。397名患者有使用REBOA的指征且无禁忌证,并有失血性休克的证据:69%为男性,中位年龄43岁,中位损伤严重程度评分为32。总体死亡率为32%。主要创伤中心(MTCs)接收的潜在REBOA患者最为集中,预计每95天会接收一名可能使用REBOA的患者,在这类损伤就诊率最高的10个MTCs中,这一频率增至每46天一名。

结论

这项TARN数据库分析确定了一小部分伤势严重、资源消耗大且损伤极具致死性的患者,理论上这些患者适合使用REBOA。这些患者在MTCs中密度最高,因此应在这些医院进一步考虑对REBOA进行有计划的评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5070/4717355/789fc1ff522d/emermed-2015-205217f01.jpg

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