Fukuoka Hideoki
Waseda University Comprehensive Research Foundation.
J Nutr Sci Vitaminol (Tokyo). 2015;61 Suppl:S2-4. doi: 10.3177/jnsv.61.S2.
Epidemiological and animal experimental studies are disclosing that the malnutrition or overnutrition in utero would induce epigenetic changes of fetus, what is the origin of lifestyle-related disease in adult. Representative birth cohorts studies in DOHaD are explained.
流行病学和动物实验研究表明,子宫内的营养不良或营养过剩会导致胎儿的表观遗传变化,这是成人生活方式相关疾病的根源。文中解释了发育起源健康与疾病研究(DOHaD)中的代表性出生队列研究。