Department of Obstetrics and Gynecology, Tokyo Medical University, Shinjuku (Tokyo), Japan.
Reprod Sci. 2024 Mar;31(3):583-590. doi: 10.1007/s43032-023-01339-0. Epub 2023 Sep 7.
Assisted reproductive technology (ART) led to the birth of 60,381 infants in 2020 in Japan. This number is set to increase as the future interest in ART is anticipated to rise. Couples receiving ART are monitoring the outcomes of these treatments to see whether any differences exist between babies conceived naturally and those conceived via ART. This study investigated the relationship between the long-term outcome of children born from ART with a focus on physical and psychomotor developments. A large volume of data concerning each relationship with ART was collected from various observational studies. Several findings indicate that, over time, the physical characteristics of babies born by ART, and those born naturally are comparable. However, some reports indicate that, until they reach school age, there may be a small difference in growth. ART and naturally conceived children do not vary in academic achievement or attention deficit hyperactivity disorder. Taken together, it is difficult to conclude with certainty that ART is the source of these differences since they may arise from the child's genetic factors or their environment.
2020 年,辅助生殖技术(ART)在日本诞生了 60381 名婴儿。随着未来对 ART 的兴趣预计会增加,这个数字还会增加。接受 ART 的夫妇正在监测这些治疗的结果,以观察自然受孕和通过 ART 受孕的婴儿之间是否存在差异。这项研究调查了与 ART 相关的儿童长期结果之间的关系,重点是身体和精神运动发育。从各种观察性研究中收集了大量与 ART 相关的各种数据。一些研究结果表明,随着时间的推移,通过 ART 出生的婴儿和自然受孕的婴儿的身体特征是可比的。然而,一些报告表明,在他们达到学龄之前,生长可能会有微小的差异。ART 受孕的儿童和自然受孕的儿童在学业成绩或注意力缺陷多动障碍方面没有差异。综合来看,由于这些差异可能来自孩子的遗传因素或环境,因此很难确定 ART 就是这些差异的根源。