Nielsen Suzanne, Campbell Gabrielle, Peacock Amy, Smith Kimberly, Bruno Raimondo, Hall Wayne, Cohen Milton, Degenhardt Louisa
National Drug and Alcohol Research Centre, UNSW, 22-32 King Street, Randwick, NSW 2031, Australia. Email:.
School of Medicine, University of Tasmania, Private Bag 30, Hobart, Tas. 7001, Australia. Email:.
Aust Health Rev. 2016 Nov;40(5):490-499. doi: 10.1071/AH15047.
Objective The aims of the present study were to describe the use, and barriers to the use, of non-medication pain therapies and to identify the demographic and clinical correlates of different non-opioid pain treatments. Methods The study was performed on a cohort (n=1514) of people prescribed pharmaceutical opioids for chronic non-cancer pain (CNCP). Participants reported lifetime and past month use of healthcare services, mental and physical health, pain characteristics, current oral morphine equivalent daily doses and financial and access barriers to healthcare services. Results Participants reported the use of non-opioid pain treatments, both before and after commencing opioid therapy. Services accessed most in the past month were complementary and alternative medicines (CAMs; 41%), physiotherapy (16%) and medical and/or pain specialists (15%). Higher opioid dose was associated with increased financial and access barriers to non-opioid treatment. Multivariate analyses indicated being younger, female and having private health insurance were the factors most commonly associated with accessing non-opioid treatments. Conclusions Patients on long-term opioid therapy report using multiple types of pain treatments. High rates of CAM use are concerning given limited evidence of efficacy for some therapies and the low-income status of most people with CNCP. Financial and insurance barriers highlight the importance of considering how different types of treatments are paid for and subsidised. What is known about the topic? Given concerns regarding long-term efficacy, adverse side-effects and risk of misuse and dependence, prescribing guidelines recommend caution in prescribing pharmaceutical opioids in cases of CNCP, typically advising a multidisciplinary approach to treatment. There is a range of evidence supporting different (non-drug) treatment approaches for CNCP to reduce pain severity and increase functioning. However, little is known about the non-opioid treatments used among those with CNCP and the demographic and clinical characteristics that may be associated with the use of different types of treatments. Understanding the use of non-drug therapy among people with CNCP is crucial given the potential to improve pain control for these patients. What does this paper add? The present study found that a wide range of non-opioid treatments was accessed by the study sample, both before and after commencing opioids, indicating that in this sample opioids were not the sole strategy used for pain management. The most common treatment (other than opioids) was CAM, reported by two-fifths of the sample. Having private health insurance was associated with increased use of non-opioid treatments for pain, highlighting the importance of considering how treatments are paid for and potential financial barriers to effective treatments. What are the implications for practitioners? Patients' beliefs and financial barriers may affect the uptake of different treatments. Many patients may be using complementary and alternative approaches with limited evidence to support their use, highlighting the need for clinicians to discuss with patients the range of prescribed and non-prescribed treatments they are accessing and to help them understand the benefits and risks of treatments that have not been tested sufficiently, or have inconsistent evidence, as to their efficacy in improving pain outcomes.
目的 本研究的目的是描述非药物疼痛治疗的使用情况及其使用障碍,并确定不同非阿片类疼痛治疗方法的人口统计学和临床相关因素。方法 本研究对一组(n = 1514)因慢性非癌性疼痛(CNCP)而开具阿片类药物处方的人群进行。参与者报告了一生中和过去一个月内使用医疗服务的情况、身心健康状况、疼痛特征、当前口服吗啡等效日剂量以及医疗服务的经济和获取障碍。结果 参与者报告在开始阿片类药物治疗之前和之后都使用了非阿片类疼痛治疗方法。过去一个月内使用最多的服务是补充和替代医学(CAMs;41%)、物理治疗(16%)以及医学和/或疼痛专科医生(15%)。较高的阿片类药物剂量与非阿片类治疗的经济和获取障碍增加有关。多变量分析表明,年龄较小、女性以及拥有私人医疗保险是与接受非阿片类治疗最常相关的因素。结论 长期接受阿片类药物治疗的患者报告使用多种类型的疼痛治疗方法。鉴于某些疗法疗效证据有限且大多数CNCP患者收入较低,CAMs的高使用率令人担忧。经济和保险障碍凸显了考虑不同类型治疗的支付方式和补贴方式的重要性。关于该主题已知的情况是什么?鉴于对长期疗效、不良副作用以及滥用和依赖风险的担忧,处方指南建议在CNCP病例中开具阿片类药物时要谨慎,通常建议采用多学科治疗方法。有一系列证据支持针对CNCP的不同(非药物)治疗方法以减轻疼痛严重程度并提高功能。然而,对于CNCP患者中使用的非阿片类治疗方法以及可能与使用不同类型治疗方法相关的人口统计学和临床特征知之甚少。鉴于有可能改善这些患者的疼痛控制,了解CNCP患者中使用非药物疗法的情况至关重要。本文补充了什么内容?本研究发现,研究样本在开始使用阿片类药物之前和之后都使用了多种非阿片类治疗方法,这表明在该样本中,阿片类药物并非用于疼痛管理的唯一策略。最常见的治疗方法(除阿片类药物外)是CAMs,五分之二的样本报告使用了该方法。拥有私人医疗保险与增加使用非阿片类疼痛治疗方法相关,这凸显了考虑治疗支付方式以及有效治疗潜在经济障碍的重要性。对从业者有何启示?患者的信念和经济障碍可能会影响不同治疗方法的采用。许多患者可能在使用补充和替代方法,但其支持证据有限,这凸显了临床医生需要与患者讨论他们正在接受的各种处方和非处方治疗方法,并帮助他们了解那些尚未经过充分测试或疗效证据不一致的治疗方法在改善疼痛结果方面的益处和风险。