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新港沙门氏菌在一名糖尿病患者中引发骨髓炎。

Salmonella newport causing osteomyelitis in a patient with diabetes.

作者信息

Weston Natasha, Moran Ed

机构信息

The Heart of England NHS Trust, Birmingham, UK.

Department of Infectious Diseases and Tropical Medicine, Birmingham Heartlands Hospital, Heart of England NHS Hospital Trust, Birmingham, UK.

出版信息

BMJ Case Rep. 2015 Nov 24;2015:bcr2015212330. doi: 10.1136/bcr-2015-212330.

Abstract

Salmonella is a foodborne pathogen that commonly causes intestinal symptoms. Bacteraemia and extraintestinal infections have been documented within the literature, and are more frequently associated with immunodeficiency and general debilitation. We discuss the case of a previously well 36-year-old man who presented with a septic knee and new-onset diabetes. Imaging confirmed osteomyelitis and a Brodie's abscess, with blood and tissue cultures revealing the isolate Salmonella enterica newport. He denied any previous gastrointestinal symptoms, recent travel, change in usual dietary habit or symptoms of diabetes. So far there have only been three reported cases of S. newport causing osteomyelitis. We discuss the incidence of Salmonella infections, including extraintestinal symptoms, its relation to immunodeficiency and the disease burden of S. newport.

摘要

沙门氏菌是一种食源性病原体,通常会引发肠道症状。文献中已记载有菌血症和肠外感染的病例,且这些感染更常与免疫缺陷和身体整体虚弱相关。我们讨论了一名此前健康的36岁男性的病例,他因膝关节化脓性感染和新发糖尿病前来就诊。影像学检查确诊为骨髓炎和布罗迪氏脓肿,血液和组织培养显示分离出肠炎沙门氏菌新港亚种。他否认之前有任何胃肠道症状、近期旅行史、饮食习惯改变或糖尿病症状。迄今为止,仅有三例关于新港沙门氏菌引起骨髓炎的报道病例。我们讨论了沙门氏菌感染的发生率,包括肠外症状、其与免疫缺陷的关系以及新港沙门氏菌的疾病负担。

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