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Origin and Functional Evolution of the Cdc48/p97/VCP AAA+ Protein Unfolding and Remodeling Machine.
J Mol Biol. 2016 May 8;428(9 Pt B):1861-9. doi: 10.1016/j.jmb.2015.11.015. Epub 2015 Dec 1.
2
An ALS disease mutation in Cdc48/p97 impairs 20S proteasome binding and proteolytic communication.
Protein Sci. 2015 Sep;24(9):1521-7. doi: 10.1002/pro.2740. Epub 2015 Jul 14.
3
Visualization of the Cdc48 AAA+ ATPase protein unfolding pathway.
Nat Commun. 2024 Aug 29;15(1):7505. doi: 10.1038/s41467-024-51835-3.
4
The Cdc48 machine in endoplasmic reticulum associated protein degradation.
Biochim Biophys Acta. 2012 Jan;1823(1):117-24. doi: 10.1016/j.bbamcr.2011.09.002. Epub 2011 Sep 16.
5
Molecular Mechanism of Substrate Processing by the Cdc48 ATPase Complex.
Cell. 2017 May 4;169(4):722-735.e9. doi: 10.1016/j.cell.2017.04.020.
6
Structure and function of the AAA+ ATPase p97/Cdc48p.
Gene. 2016 May 25;583(1):64-77. doi: 10.1016/j.gene.2016.02.042. Epub 2016 Mar 3.
7
Structure and functions of the chaperone-like p97/CDC48 in plants.
Biochim Biophys Acta Gen Subj. 2017 Jan;1861(1 Pt A):3053-3060. doi: 10.1016/j.bbagen.2016.10.001. Epub 2016 Oct 4.
8
Valosin-containing protein (VCP/p97) is capable of unfolding polyubiquitinated proteins through its ATPase domains.
Biochem Biophys Res Commun. 2015 Jul 31;463(3):453-7. doi: 10.1016/j.bbrc.2015.05.111. Epub 2015 Jun 1.
9
ATP-binding sites in brain p97/VCP (valosin-containing protein), a multifunctional AAA ATPase.
Biochem J. 2003 Sep 1;374(Pt 2):473-80. doi: 10.1042/BJ20030219.
10
Cdc48/p97, a key actor in the interplay between autophagy and ubiquitin/proteasome catabolic pathways.
Biochim Biophys Acta. 2012 Jan;1823(1):138-44. doi: 10.1016/j.bbamcr.2011.07.011. Epub 2011 Jul 23.

引用本文的文献

2
Valosin-Containing Protein (VCP)/p97 Oligomerization.
Subcell Biochem. 2024;104:485-501. doi: 10.1007/978-3-031-58843-3_18.
4
Allosteric activation of VCP, an AAA unfoldase, by small molecule mimicry.
Proc Natl Acad Sci U S A. 2024 Jun 11;121(24):e2316892121. doi: 10.1073/pnas.2316892121. Epub 2024 Jun 4.
7
Cellular differentiation into hyphae and spores in halophilic archaea.
Nat Commun. 2023 Apr 1;14(1):1827. doi: 10.1038/s41467-023-37389-w.
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Autophagy and white spot syndrome virus infection in crustaceans.
Fish Shellfish Immunol Rep. 2021 Dec 18;3:100047. doi: 10.1016/j.fsirep.2021.100047. eCollection 2022 Dec.
9
Structural dynamics of AAA + ATPase Drg1 and mechanism of benzo-diazaborine inhibition.
Nat Commun. 2022 Nov 9;13(1):6765. doi: 10.1038/s41467-022-34511-2.
10
Distinct mRNA and protein interactomes highlight functional differentiation of major eIF4F-like complexes from .
Front Mol Biosci. 2022 Oct 7;9:971811. doi: 10.3389/fmolb.2022.971811. eCollection 2022.

本文引用的文献

1
Dissection of Axial-Pore Loop Function during Unfolding and Translocation by a AAA+ Proteolytic Machine.
Cell Rep. 2015 Aug 11;12(6):1032-41. doi: 10.1016/j.celrep.2015.07.007. Epub 2015 Jul 30.
2
An ALS disease mutation in Cdc48/p97 impairs 20S proteasome binding and proteolytic communication.
Protein Sci. 2015 Sep;24(9):1521-7. doi: 10.1002/pro.2740. Epub 2015 Jul 14.
3
Molecular snapshots of the Pex1/6 AAA+ complex in action.
Nat Commun. 2015 Jun 12;6:7331. doi: 10.1038/ncomms8331.
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Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis.
Cell. 2015 May 7;161(4):858-67. doi: 10.1016/j.cell.2015.04.017.
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Spring-loaded unraveling of a single SNARE complex by NSF in one round of ATP turnover.
Science. 2015 Mar 27;347(6229):1485-9. doi: 10.1126/science.aaa5267.
6
The Pex1/Pex6 complex is a heterohexameric AAA+ motor with alternating and highly coordinated subunits.
J Mol Biol. 2015 Mar 27;427(6 Pt B):1375-1388. doi: 10.1016/j.jmb.2015.01.019. Epub 2015 Feb 7.
7
Coordinated gripping of substrate by subunits of a AAA+ proteolytic machine.
Nat Chem Biol. 2015 Mar;11(3):201-6. doi: 10.1038/nchembio.1732. Epub 2015 Jan 19.
8
Mechanistic insights into the recycling machine of the SNARE complex.
Nature. 2015 Feb 5;518(7537):61-7. doi: 10.1038/nature14148. Epub 2015 Jan 12.
9
Evaluating p97 inhibitor analogues for their domain selectivity and potency against the p97-p47 complex.
ChemMedChem. 2015 Jan;10(1):52-6. doi: 10.1002/cmdc.201402420. Epub 2014 Nov 6.
10
Key steps in ERAD of luminal ER proteins reconstituted with purified components.
Cell. 2014 Sep 11;158(6):1375-1388. doi: 10.1016/j.cell.2014.07.050.

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