Brown C E, Wendel G D
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75235-9032.
Clin Obstet Gynecol. 1989 Mar;32(1):89-102. doi: 10.1097/00003081-198903000-00012.
Arrhythmias of the pregnant patient are rare. In most cases, the therapeutic agent chosen should be much the same as that in the nonpregnant patient, and an understanding of the pharmacology of the antiarrhythmic agents is necessary for rational use in the pregnant patient with an arrhythmia. Substantial experience has been accumulated using some of the older agents for treatment of arrhythmias in pregnancy. As newer agents become available, there may be indications for their use in pregnancy; however, we recommend initially using well-known drugs until more experience is gained with the newer ones. The choice of an agent should be made only after thorough evaluation of the patient's symptoms, accurate diagnosis and an analysis of potential benefit versus potential risk to the mother or fetus.
妊娠患者的心律失常很少见。在大多数情况下,所选用的治疗药物应与非妊娠患者基本相同,了解抗心律失常药物的药理学知识对于合理治疗妊娠合并心律失常的患者很有必要。在使用一些较老的药物治疗妊娠心律失常方面已经积累了丰富的经验。随着更新的药物问世,它们可能有用于妊娠的指征;然而,我们建议在对新药有更多经验之前,最初先使用知名药物。只有在对患者的症状进行全面评估、准确诊断并分析对母亲或胎儿的潜在益处与潜在风险之后,才能做出药物选择。