Vuichoud Camille, Klap Julia, Loughlin Kevin R
Division of Urology, Brigham and Women's Hospital, Harvard Medical School, 45 Francis Street, Boston, MA 02115, USA.
Division of Urology, Brigham and Women's Hospital, Harvard Medical School, 45 Francis Street, Boston, MA 02115, USA.
Urol Clin North Am. 2016 Feb;43(1):135-43. doi: 10.1016/j.ucl.2015.08.012.
Penile cancer is a rare malignancy, which can be a source of devastating psychosexual distress because of its implication on sexual function and self-image. Current penile staging relies on invasive techniques and is often inaccurate. The authors review the promising biomarkers currently under investigation and their application to the staging and prognosis of penile cancer. Further development of such biomarkers provides the potential of improved clinical management of this disease.
阴茎癌是一种罕见的恶性肿瘤,因其对性功能和自我形象的影响,可能成为严重心理性困扰的根源。目前阴茎癌分期依赖侵入性技术,且常常不准确。作者回顾了目前正在研究的有前景的生物标志物及其在阴茎癌分期和预后中的应用。此类生物标志物的进一步发展为改善该疾病的临床管理提供了潜力。