Dale Rebecca, Stacey Brett
Harborview Medical Center, Anesthesiology and Pain Medicine, Box 359724, 325 Ninth Ave, Seattle, WA 98104, USA.
Anesthesiology and Pain Medicine, UW Center for Pain Relief, University of Washington, 4225 Roosevelt Way Northeast, Box 354693, Seattle, WA 98105, USA.
Med Clin North Am. 2016 Jan;100(1):55-64. doi: 10.1016/j.mcna.2015.08.012. Epub 2015 Oct 17.
Most patients with chronic pain receive multimodal treatment. There is scant literature to guide us, but when approaching combination pharmacotherapy, the practitioner and patient must weigh the benefits with the side effects; many medications have modest effect yet carry significant side effects that can be additive. Chronic pain often leads to depression, anxiety, and deconditioning, which are targets for treatment. Structured interdisciplinary programs are beneficial but costly. Interventions have their place in the treatment of chronic pain and should be a part of a multidisciplinary treatment plan. Further research is needed to validate many common combination treatments.
大多数慢性疼痛患者接受多模式治疗。可供指导我们的文献很少，但在采用联合药物治疗时，从业者和患者必须权衡益处与副作用；许多药物效果一般，但会带来显著的副作用，且这些副作用可能会叠加。慢性疼痛常导致抑郁、焦虑和身体机能下降，这些都是治疗的目标。结构化的跨学科项目有益但成本高昂。干预措施在慢性疼痛治疗中占有一席之地，应成为多学科治疗计划的一部分。需要进一步研究来验证许多常见的联合治疗方法。
