混合群体正向时间模拟的灵活框架，具有选择和配偶选择。
Admix'em: a flexible framework for forward-time simulations of hybrid populations with selection and mate choice.
机构信息
Department of Biology, Texas A&M University, College Station, TX 77843, USA, Centro De Investigaciones Científicas De Las Huastecas "Aguazarca", Calnali, Mexico and Max Planck Institute for the Biology of Aging, Cologne, Germany.
Centro De Investigaciones Científicas De Las Huastecas "Aguazarca", Calnali, Mexico and.
出版信息
Bioinformatics. 2016 Apr 1;32(7):1103-5. doi: 10.1093/bioinformatics/btv700. Epub 2015 Nov 28.
UNLABELLED
We introduce a new forward-time simulator, Admix'em, that allows for rapid and realistic simulations of admixed populations with selection. Complex selection can be achieved through user-defined fitness and mating-preference probability functions. Users can specify realistic genomic landscapes and model neutral SNPs in addition to sites under selection. Admix'em is designed to simulate selection in admixed populations but can also be used as a general population simulator. Usage and examples are in the supplement.
AVAILABILITY AND IMPLEMENTATION
C ++ and OpenMP, supports 64-bit Linux/Unix-like platforms. https://github.com/melop/admixem
CONTACT
SUPPLEMENTARY INFORMATION
Supplementary data are available at Bioinformatics online.
未加标签
我们引入了一个新的正向时间模拟器 Admix'em，它允许对具有选择的混合群体进行快速和真实的模拟。复杂的选择可以通过用户定义的适应度和交配偏好概率函数来实现。用户可以指定现实的基因组景观，并在选择的位置之外模拟中性 SNPs。Admix'em 旨在模拟混合群体中的选择，但也可以用作一般群体模拟器。用法和示例在补充材料中。
可用性和实现
C++和 OpenMP，支持 64 位 Linux/Unix 类似平台。https://github.com/melop/admixem
联系人
补充信息
补充数据可在生物信息学在线获得。
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