Razak Abdul, Mohanty Pankaj Kumar, Nagesh N Karthik
Department of Neonatology, Manipal Hospital. Bangalore, India. Correspondence to: Dr N Karthik Nagesh, Head, Department of Neonatology, Manipal Group of Hospitals, Bangalore, India.
Indian Pediatr. 2015 Nov;52(11):984-6. doi: 10.1007/s13312-015-0759-y.
Persistent pulmonary hypertension (PPHN) in a term or late preterm has varied etiology.
A late preterm neonate operated for esophageal atresia with tracheo-esophageal fistula was complicated by severe pulmonary hypertension and unable to be weaned off from respiratory support.
The neonate expired by 15 weeks of life; diagnosis was made on postmortem lung biopsy.
Alveolarcapillary dysplasia should be considered in a neonate with idiopathic refractory PPHN, if associated with anomalies.
足月儿或晚期早产儿持续性肺动脉高压（PPHN）病因多样。
一名晚期早产儿因食管闭锁合并气管食管瘘接受手术，并发严重肺动脉高压，无法撤机。
该新生儿在15周龄时死亡；死后肺活检确诊。
对于患有特发性难治性PPHN且伴有畸形的新生儿，应考虑肺泡毛细血管发育不良。
