硫唑嘌呤治疗期间的急性白血病。
Acute leukaemia during azathioprine therapy.
作者信息
Gilmore I T, Holden G, Rodan K S
出版信息
Postgrad Med J. 1977 Mar;53(617):173-4. doi: 10.1136/pgmj.53.617.173.
Abstract
Various tumours, in particular lymphomas, have been reported in association with azathioprine treatment, both after renal transplantation and in other conditions. A case is reported here of acute myeloid leukaemia associated with azathioprine therapy for rheumatoid arthritis, and this is now the third case reported in the world literature of leukaemia arising during azathioprine therapy for a non-malignant condition.
摘要
据报道，在肾移植后以及其他情况下，多种肿瘤，尤其是淋巴瘤，与硫唑嘌呤治疗有关。本文报告了1例与硫唑嘌呤治疗类风湿关节炎相关的急性髓系白血病病例，这是世界文献中报道的第3例在硫唑嘌呤治疗非恶性疾病期间发生白血病的病例。
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本文引用的文献
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AN ASSOCIATION BETWEEN THE RHEUMATIC DISEASES AND THE RETICULOSES.风湿性疾病与网状内皮系统疾病之间的关联。
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Immunosurveillance and cancer: epidemiological evidence.免疫监视与癌症：流行病学证据
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Azathioprine (Imuran) administration and the development of malignant lymphomas in NZB mice.硫唑嘌呤（依木兰）给药与NZB小鼠恶性淋巴瘤的发生
Clin Exp Immunol. 1968 May;3(4):305-12.
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Immunosurveillance and cancer.免疫监视与癌症
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Immmunosuppressive drugs in the treatment of autoimmune haemolytic anaemia.免疫抑制药物治疗自身免疫性溶血性贫血
Proc R Soc Med. 1968 Dec 12;61(12):1312-5. doi: 10.1177/003591576806101237.
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