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瑞典目前的糖尿病患病率及2050年预测

Diabetes Prevalence in Sweden at Present and Projections for Year 2050.

作者信息

Andersson Tomas, Ahlbom Anders, Carlsson Sofia

机构信息

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Center for Occupational and Environmental Medicine, Stockholm County Council, Stockholm, Sweden.

出版信息

PLoS One. 2015 Nov 30;10(11):e0143084. doi: 10.1371/journal.pone.0143084. eCollection 2015.

Abstract

BACKGROUND

Data on the future diabetes burden in Scandinavia is limited. Our aim was to project the future burden of diabetes in Sweden by modelling data on incidence, prevalence, mortality, and demographic factors.

METHOD

To project the future burden of diabetes we used information on the prevalence of diabetes from the national drug prescription registry (adults ≥ 20 years), previously published data on relative mortality in people with diabetes, and population demographics and projections from Statistics Sweden. Alternative scenarios were created based on different assumptions regarding the future incidence of diabetes.

RESULTS

Between 2007 and 2013 the prevalence of diabetes rose from 5.8 to 6.8% in Sweden but incidence remained constant at 4.4 per 1000 (2013). With constant incidence and continued improvement in relative survival, prevalence will increase to 10.4% by year 2050 and the number of afflicted individuals will increase to 940 000. Of this rise, 30% is accounted for by changes in the age structure of the population and 14% by improved relative survival in people with diabetes. A hypothesized 1% annual rise in incidence will result in a prevalence of 12.6% and 1 136 000 cases. Even with decreasing incidence at 1% per year, prevalence of diabetes will continue to increase.

CONCLUSION

We can expect diabetes prevalence to rise substantially in Sweden over the next 35 years as a result of demographic changes and improved survival among people with diabetes. A dramatic reduction in incidence is required to prevent this development.

摘要

背景

斯堪的纳维亚半岛未来糖尿病负担的数据有限。我们的目的是通过对发病率、患病率、死亡率和人口统计学因素的数据进行建模,预测瑞典未来的糖尿病负担。

方法

为了预测未来的糖尿病负担,我们使用了来自国家药物处方登记处(20岁及以上成年人)的糖尿病患病率信息、先前发表的糖尿病患者相对死亡率数据,以及瑞典统计局的人口统计学和预测数据。基于对未来糖尿病发病率的不同假设创建了替代情景。

结果

2007年至2013年期间,瑞典糖尿病患病率从5.8%升至6.8%,但发病率保持在每1000人4.4例(2013年)不变。随着发病率不变以及相对生存率持续改善,到2050年患病率将增至10.4%,患病个体数量将增至94万。在这一增长中,30%是由人口年龄结构变化导致的,14%是由糖尿病患者相对生存率提高导致的。假设发病率每年上升1%,将导致患病率达到12.6%,病例数达到113.6万。即使发病率以每年1%的速度下降,糖尿病患病率仍将继续上升。

结论

由于人口结构变化和糖尿病患者生存率提高,我们预计瑞典在未来35年糖尿病患病率将大幅上升。需要大幅降低发病率以防止这种情况的发展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c8a/4664416/d3e0a1a9ea5a/pone.0143084.g001.jpg

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