Fan Chengming, Gao Zibo, Yin N I, Yang Jinfu
Department of Cardiothoracic Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China.
Oncol Lett. 2015 Oct;10(4):2071-2074. doi: 10.3892/ol.2015.3529. Epub 2015 Jul 23.
In order to review the surgical experience of a single institute with regard to the treatment of primary cardiac tumors, data was collected on patients with a histopathological diagnosis of a primary cardiac tumor (with the exception of myxoma) in a retrospective analysis of those treated between 2004 and 2013. In total, 11 patients were identified, with a mean age at diagnosis of 23 months and a mean weight of 13 kg. The most frequent cause of referral was a cardiac murmur and the most frequent cardiac tumor was rhabdomyoma (5 cases), followed by fibroma (3 cases), angiofibroma (2 cases) and fibrosarcoma (1 case). Surgical removal of the tumor was performed in all patients due to the respective clinical symptoms. A subtotal resection was performed in a single patient (with angiofibroma invading the aortic root, superior vena cava and sinus node) due to financial constraints. This patient succumbed to tumor invasion 2 years later. Another of the patients (pericardial fibrosarcoma) succumbed 1 year after the total resection, as they were unable to undergo a repeat surgery for the relapsed tumor due to financial inadequacy. The remaining 9 patients have survived in good condition during the 1-6 year follow-up. Surgery is the preferred treatment for patients with symptomatic primary cardiac tumors, and has good early- and long-term outcomes. However, due to the current health care system inadequacies in China, certain parents cannot afford the medical expenses, thus, more comprehensive social security and medical insurance may require consideration.
为回顾某单一机构治疗原发性心脏肿瘤的手术经验,我们对2004年至2013年间接受治疗的患者进行了回顾性分析,收集了组织病理学诊断为原发性心脏肿瘤(黏液瘤除外)患者的数据。总共确定了11例患者,诊断时的平均年龄为23个月,平均体重为13千克。最常见的转诊原因是心脏杂音,最常见的心脏肿瘤是横纹肌瘤(5例),其次是纤维瘤(3例)、血管纤维瘤(2例)和纤维肉瘤(1例)。由于各自的临床症状,所有患者均接受了肿瘤手术切除。由于经济限制,1例患者(血管纤维瘤侵犯主动脉根部、上腔静脉和窦房结)进行了次全切除。该患者2年后死于肿瘤侵袭。另1例患者(心包纤维肉瘤)在全切除术后1年死亡,因为他们因经济不足无法对复发肿瘤进行再次手术。其余9例患者在1至6年的随访中状况良好地存活下来。手术是有症状的原发性心脏肿瘤患者首选的治疗方法,具有良好的早期和长期疗效。然而,由于中国目前医疗保健系统的不足,某些家长负担不起医疗费用,因此,可能需要考虑更全面的社会保障和医疗保险。