Macedo Guilherme, Lopes Susana, Peixoto Armando
Gastroenterology Department, Centro Hospitalar de São João, Faculty of Medicine, University of Porto, Porto, Portugal.
J Clin Gastroenterol. 2016 Oct;50(9):769-71. doi: 10.1097/MCG.0000000000000453.
Inorganic lead intoxication has emerged as an important and challenging clinical problem owing to increased awareness of lead and enhanced surveillance of exposed individuals. However, recognition may not be very difficult when there is an obvious history of exposure. Our interest began a few years ago when we could trace an outbreak, following a patient who was admitted with colickly abdominal pain, convulsions, and coma. After that, 16 more cases were identified and characterized. All patients recovered completely after adequate chelation therapy. Although the clinical picture of lead intoxication is pleomorphic, the increased awareness of gastroenterologists in this subject may possibly bring chronically complaining difficult patients to an earlier, unexpected, and fairly treatable disease.
由于对铅的认识增加以及对暴露个体的监测加强，无机铅中毒已成为一个重要且具有挑战性的临床问题。然而，当有明显的接触史时，诊断可能并不十分困难。我们的兴趣始于几年前，当时我们追踪到一次疫情爆发，起因是一名患者因绞痛性腹痛、抽搐和昏迷入院。此后，又确诊并描述了另外16例病例。所有患者在接受充分的螯合治疗后完全康复。尽管铅中毒的临床表现多种多样，但胃肠病学家对该主题认识的提高可能会使长期抱怨的疑难患者更早地被诊断出一种意想不到且相当可治的疾病。
