Kaneko Masahiko, Kazatani Takurou, Shikata Hisaharu
Department of Internal Medicine, Uwajima City Hospital, Japan.
Department of General Medicine, Ehime Prefectural Central Hospital, Japan.
Intern Med. 2020;59(12):1565-1570. doi: 10.2169/internalmedicine.4176-19. Epub 2020 Jun 15.
We herein report a 24-year-old male construction worker with occupational lead poisoning who presented with acute abdomen and normocytic anemia. The levels of urinary delta-aminolevulinic acid and free erythrocyte protoporphyrin were elevated without any increase in the level of urine porphobilinogen. Detection of an elevated blood lead level of 100 μg/dL confirmed a diagnosis of lead poisoning. Chelation therapy with calcium disodium ethylenediaminetetraacetate resulted in prompt improvement of the clinical symptoms and the blood lead level. Clinicians should be aware that lead poisoning caused by occupational exposure can still occur sporadically in construction workers in Japan.
我们在此报告一名24岁的男性建筑工人，患有职业性铅中毒，表现为急腹症和正细胞性贫血。尿δ-氨基乙酰丙酸和游离红细胞原卟啉水平升高，而尿卟胆原水平无任何升高。血铅水平升高至100μg/dL证实了铅中毒的诊断。用依地酸钙钠进行螯合治疗后，临床症状和血铅水平迅速改善。临床医生应意识到，在日本，职业接触导致的铅中毒仍可能在建筑工人中偶尔发生。
