免疫球蛋白G4相关性肾小管间质性肾炎

Immunoglobulin G4 related tubulointerstitial nephritis.

作者信息

Nithyashree N, Rajagopalan S, Annigeri R A, Mani R

机构信息

Department of Nephrology, Apollo Hospital, Chennai, Tamil Nadu, India.

Department of Pathology, Apollo Hospital, Chennai, Tamil Nadu, India.

出版信息

Indian J Nephrol. 2015 Sep-Oct;25(5):303-6. doi: 10.4103/0971-4065.152725.

DOI:10.4103/0971-4065.152725

PMID:26628798

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4588328/

Abstract

Tubulointerstitial nephritis is an uncommon manifestation of IgG4 related disease. A case of tubulointerstitial nephritis with special features including isolated renal involvement in this multisystem disorder and the absence of response to steroid therapy in a young male is reported here. There was no nephromegaly, eosinophilia or other organ involvement. The importance of early detection and treatment for preservation of kidney function is highlighted.

摘要

肾小管间质性肾炎是IgG4相关疾病的一种罕见表现。本文报道了一例具有特殊特征的肾小管间质性肾炎病例，该病例为一名年轻男性，患有这种多系统疾病，仅累及肾脏，且对类固醇治疗无反应。患者无肾肿大、嗜酸性粒细胞增多或其他器官受累。强调了早期检测和治疗对于保护肾功能的重要性。