Jahangiri Faisal R
Neurodiagn J. 2015 Sep;55(3):169-79. doi: 10.1080/21646821.2015.1071142.
This case illustrates the benefits of utilizing intraoperative neurophysiological monitoring (IONM) for preventing injury to sensory/motor pathways of the spinal cord during a cordotomy procedure to relieve pain. Cordotomy has been used effectively in the treatment of visceral pain but comes with a high risk of damaging motor and sensory pathways due to close proximity of lesion. The subject is a 47-year-old female with a pancoast tumor of the left lung, left brachialplexopathy, and severe neuropathic pain syndrome, refractory to medical therapy. A palliative cordotomy procedure was elected for pain control. Baseline bilateral posterior tibial and median nerve somatosensory evoked potentials (SSEP) were present except in the left upper extremity. Transcranial electric motor evoked potential (TCeMEP) baselines were present in all extremities except the left upper. Total intravenous anesthesia was used. The spine was exposed at C2-C3 and a right single anterolateral cordotomy was performed with an immediate drop in TCeMEPs (70-80% amplitude reduction) in the right upper and right lower extremities. The surgeon decided to stop the cordotomy at that point. Postoperatively, the patient had no sensory or motor deficit. In this patient, TCeMEPs were used effectively to guide the surgeon in preventing damage to the spinal cord that could lead to motor deficits.
本病例说明了在脊髓前侧柱切断术缓解疼痛过程中,利用术中神经生理监测(IONM)预防脊髓感觉/运动通路损伤的益处。脊髓前侧柱切断术已有效地用于治疗内脏疼痛,但由于病变位置临近,存在损伤运动和感觉通路的高风险。该患者为一名47岁女性,患有左肺潘科斯特瘤、左臂丛神经病变以及严重的神经性疼痛综合征,药物治疗无效。为控制疼痛选择了姑息性脊髓前侧柱切断术。除左上肢外,双侧胫后神经和正中神经体感诱发电位(SSEP)基线存在。除左上肢外,所有肢体均有经颅电刺激运动诱发电位(TCeMEP)基线。采用全静脉麻醉。在C2 - C3水平暴露脊柱,进行了右侧单次脊髓前侧柱切断术,术后右上肢和右下肢的TCeMEP立即下降(波幅降低70 - 80%)。外科医生当时决定停止脊髓前侧柱切断术。术后,患者无感觉或运动功能缺损。在该患者中,TCeMEP有效地用于指导外科医生预防可能导致运动功能缺损的脊髓损伤。