多灶性广泛耐药结核性骨髓炎的成功治疗。

Successful treatment of multi-focal XDR tuberculous osteomyelitis.

作者信息

Alshukairi Abeer N, Alrajhi Abdulrahman A, Alamri Abdulfattah W, Alothman Adel F

机构信息

King Faisal Specialist Hospital and Research Centre, Department of Internal Medicine, PO BOX 40047, Jeddah 21499, Saudi Arabia.

King Faisal Specialist Hospital and Research Center, Department of Internal Medicine, PO BOX 3354, Riyadh 11211, Saudi Arabia.

出版信息

J Infect Public Health. 2016 Jul-Aug;9(4):408-14. doi: 10.1016/j.jiph.2015.10.010. Epub 2015 Nov 27.

DOI:10.1016/j.jiph.2015.10.010

PMID:26631433

Abstract

We herein describe the nosocomial transmission of a pre-XDR or MDR case of pulmonary tuberculosis in a HIV-negative health care worker in an area endemic for MDR and XDR tuberculosis. Following inadequate therapy and non-compliance, he presented with extra-pulmonary XDR tuberculosis in the form of multi-focal osteomyelitis and encysted pleural effusion. He was cured after two years of treatment with various anti-tuberculous drugs in addition to interferon gamma.

摘要

我们在此描述了在耐多药和广泛耐药结核病流行地区，一名HIV阴性医护人员发生的广泛耐药前或耐多药肺结核的医院内传播情况。在治疗不充分且患者不依从之后，他出现了肺外广泛耐药结核病，表现为多灶性骨髓炎和包裹性胸腔积液。除γ干扰素外，他在接受了两年的各种抗结核药物治疗后治愈。