Lavoie R R, McDonald J R, Kling G A
Acta Cytol. 1977 Mar-Apr;21(2):210-4.
This study indicates that a good percentage of the cavitary squamous cell carcinomas of the lung can be suggested throught the use of sputum cytology. Hyperkeratinized malignant cells associated with varying degrees of karyorrhexis, "ghost cells," and a diathesis of purulent exudate are helpful in the identification of this tumor type. The cell population found cytologically can be demonstrated in the histologic sections of cavitary squamous cell carcinoma of the lung. We readily admit that the application of the above criteria will not decrease the mortality or morbidity of lung cancer, but can be used as a refinement of a diagnostic tool.
本研究表明，通过痰液细胞学检查可以提示相当比例的肺空洞性鳞状细胞癌。伴有不同程度核溶解的角化过度恶性细胞、“鬼影细胞”以及脓性渗出素质有助于识别这种肿瘤类型。细胞学检查发现的细胞群体可以在肺空洞性鳞状细胞癌的组织学切片中得到证实。我们欣然承认，应用上述标准不会降低肺癌的死亡率或发病率，但可用作诊断工具的一种优化。
